A Novel Biomineralized Collagen Liquid Crystal Hydrogel Possessing Bone-like Nanostructures by Complete In Vitro Fabrication
The microstructure of bone consists of nano-hydroxyapatite (nano-HA) crystals aligned within the interspaces of collagen fibrils.To emulate this unique microstructure of bone, this work applied two biomimetic techniques to obtain bone-like microstructures in vitro, that is, combining the construction of collagen liquid crystal hydrogel Condom (CLCH